Perhaps more so than ever before, the world desperately needs critical thinkers, creative problem solvers, and curious scientists. This is true in every aspect of our culture and in every sector of society. Whether it is in academia, government, business, media, or non-profit; critical, evidence based reasoning and creative problem solving is clearly an asset to every organization and to the world. As a science teacher, my responsibility is to encourage every student’s innate curiosity, ignite their imagination, and inspire the continuous pursuit of knowledge. Higher level knowledge occurs when students can begin to apply the concepts, analyze, and evaluate why certain phenomena occur or exist; ultimately using their knowledge to explore and create novel ideas and insights. This is my purpose as a science teacher: to provide the platform for students to explore big scientific questions, to be independent critical thinkers, and to become creative problem solvers.
Jones A.M., Kirby B.S., Clark I.E., Rice H.M., Fulkerson E., Wylie L.J., Wilkerson D.P., Vanhatalo A., Wilkins B.W. Physiological Demands of Running a 2-Hour Marathon Race Pace. J Appl Physiol. 2020 DOI:10.1152/japplphysiol.00647.2020
Clark I.E., Vanhatalo A., Thompson C., Joseph C, Black M.I., Blackwell J.R., Wylie L.J., Tan R., Bailey S.J., Wilkins B.W., Kirby B.S., Jones A.M. Dynamics of the power-duration relationship during prolonged endurance exercise and influence of carbohydrate ingestion. J Appl Physiol. 2019 Sep 1;127(3):726-736.
Clark I.E., Vanhatalo A., Thompson C., Wylie L.J., Bailey S.J., Kirby B.S., Wilkins B.W., Jones A.M. Changes in the power-duration relationship following prolonged exercise: estimation using conventional and all-out protocols and relationship with muscle glycogen. Am J Physiol Regul Integr Comp Physiol. 2019 Jul 1;317(1):R59-R67.
Kirby B.S., Bradley E.M., Wilkins B.W. Critical Velocity during Intermittent Running with Changes of Direction. Med Sci Sports Exerc. 2019 Feb;51(2):308-314.
Clark, I.E., Vanhatalo, A., Bailey, S.J., Wylie, L.J., Kirby, B.S., Wilkins, B.W., Jones, A.M. Effects of Two Hours of Heavy-Intensity Exercise on the Power-Duration Relationship. Med Sci Sports Exerc. 2018 Aug;50(8):1658-1668.
Limberg, J.K., Malterer, K.R., Mikhail Kellawan, J., Schrage, W.G., Wilkins, B.W., Nicholson, W.T., Eisenach, J.H., Joyner, M.J., and T.B. Curry. Potentiation of the NO-cGMP pathway and blood flow responses during dynamic exercise in healthy humans. Eur J Appl Physiol. 117(2):237-246, 2017.
Wheatley, C.M., Wilkins, B.W., and E.M. Snyder. Exercise as Medicine in Cystic Fibrosis. Exerc Sport Sci Rev. 39(3):155-60, 2011.
Casey, D.P., Curry, T.B., Wilkins, B.W., and M.J. Joyner. Nitric oxide mediated vasodilatation becomes independent of β-adrenergic receptor activation with increased intensity of hypoxic exercise. J Appl Physiol. 110(3):687-94, 2011.
Wilkins, B.W. Bring on the heat: transient receptor potential vanilloid type-1 (TRPV-1) channels as a sensory link for local thermal hyperaemia. J Physiol. 588 (21): 4065, 2010.
Schrage, W.G., Wilkins, B.W., Johnson, C.P., Eisenach, J.H., Limberg, J.K., Dietz, N.M., Curry, T.B., and M.J. Joyner. Roles of nitric oxide synthase and cyclooxygenase in leg vasodilation and oxygen consumption during prolonged low-intensity exercise in untrained humans. J Appl Physiol. 109 (3):768-777, 2010.
Casey, D.P., Madery, B.D., Curry, T.B., Eisenach, J.H., Wilkins, B.W., and M.J. Joyner. Nitric oxide contributes to augmented vasodilatation during hypoxic exercise. J Physiol. 15 (588; Pt 2):373-385, 2010.
Casey, D.P., Madery, B.D., Pike, T.L., Eisenach, J.H., Dietz, N.M., Joyner, M.J. and B.W. Wilkins. Adenosine receptor antagonists and augmented vasodilation during hypoxic exercise. J Appl Physiol. 107(4):1128-37, 2009.
Wilkins, B.W. Invited commentary on “the human cutaneous circulation as a model of generalized microvascular function”. J Appl Physiol. 105(1): 374-375, 2008.
Wilkins, B.W., Pike, T.L., Martin, E.A., Curry, T.B., Ceridon, M.L. and M.J. Joyner. Exercise intensity dependent contribution of β-adrenergic receptor mediated vasodilatation in hypoxic humans. J Physiol. 586(4): 1195-1205, 2008.
Wilkins, B.W., Hesse, C., Charkoudian, N., Nicholson, W.T., Sviggum, H.P., Moyer, T.P., Joyner, M.J. and J.H. Eisenach. Autonomic cardiovascular control during a novel pharmacological alternative to ganglionic blockade. Clin Pharm Ther. 83(5): 692-701, 2008.
Masuki, S., Eisenach, J.E., Schrage, W.G., Dietz, N.M., Johnson, C.P., Wilkins, B.W., Dierkhising, R.A., Sandroni, P., Low, P.A., and M.J. Joyner. Arterial baroreflex control of heart rate during exercise in postural tachycardia syndrome. J Appl Physiol. 103(4):1136-1142, 2007.
Joyner, M.J. and B.W. Wilkins. Exercise Hyperaemia: is anything obligatory but the hyperaemia? J Physiol. 583(pt 3): 855-60, 2007.
Masuki, S., Eisenach, J.E., Schrage, W.G., Johnson, C.P., Dietz, N.M., Wilkins, B.W., Sandroni, P., Low, P.A., and M.J. Joyner. Reduced stroke volume during exercise in postural tachycardia syndrome. J Appl Physiol. 103(4):1128-1135, 2007.
Wilkins, B.W., Martin E.A., Roberts, S.K., and M.J. Joyner. Preserved reflex cutaneous vasodilation in cystic fibrosis does not include an enhanced nitric oxide dependent mechanism. J Appl Physiol. 02(6):2301-2306, 2007.
Wilkins, B.W., Hesse, C., Sviggum, H.P., Nicholson, W.T., Moyer, T.P., Joyner, M.J. and J.H. Eisenach. Alternative to ganglionic blockade with anticholinergic and alpha-2 receptor agents. Clin Auton Res. 17(2):77-84, 2007.
Solkolnicki, L. A., Roberts, S.K., Wilkins, B.W., Basu, A. and N. Charkoudian. Contribution of nitric oxide to cutaneous microvascular dilation in individuals with type 2 diabetes mellitus. Am J Physiol Endocrinol Metab. 292(1):E314-318, 2007.
Wilkins, B.W., Schrage, W.G., Liu, Z., Hancock, K.C., and M.J. Joyner. Systemic hypoxia and vasoconstrictor responsiveness in exercising human muscle. J Appl Physiol. 101(5): 1343-1350, 2006.
Wilkins, B.W., Wong, B.J., Tublitz, N.J., McCord, G.R. and C.T. Minson. Vasoactive intestinal peptide fragment VIP10-28 and active vasodilation in human skin. J Appl Physiol. 99(6): 2294-2301, 2005.
Schrage, W.G., Wilkins, B.W., Dean, V.L., Scott, J.P., Henry, N.K., Wylam, M.E. and M.J. Joyner. Exercise hyperemia and vasoconstrictor responses in humans with cystic fibrosis. J Appl Physiol. 99(5): 1866-1871, 2005.
Lockwood, J.M., Wilkins, B.W. and J.R. Halliwill. H1 receptor-mediated vasodilatation contributes to postexercise hypotension. J Physiol. 563(pt 2): 633-642, 2005.
Lockwood, J.M., Pricher, M.P., Wilkins, B.W., Holowatz, L.A. and J.R. Halliwill. Postexercise hypotension is not explained by a prostaglandin-dependent peripheral vasodilation. J Appl Physiol. 98(2): 447-453, 2005.
Wong, B.J., Wilkins, B.W. and C.T. Minson. H1 but not H2 receptor activation contributes to the rise in skin blood flow during whole body heating in humans. J Physiol. 560(pt 3): 941-948, 2004.
Wilkins, B.W., Minson, C.T. and J.R. Halliwill. Regional hemodynamics during postexercise hypotension. II. Cutaneous circulation. J Appl Physiol. 97(6): 2071-2076, 2004.
Wilkins, B.W., Chung, L.H., Tublitz, N.J. and C.T. Minson. Mechanisms of vasoactive intestinal peptide-mediated vasodilation in human skin. J Appl Physiol. 97(4): 1291-1298, 2004.
Watts, P.B., Joubert, L.M., Lish, A.K., Mast, J.D. and B.W. Wilkins. Anthropometry of young competitive sport rock climbers. Br J Sports Med. 37(5): 420-424, 2003.
Wong, B.J., Wilkins, B.W., Holowatz, L.A. and C.T. Minson. Nitric oxide synthase inhibition does not alter the reactive hyperemia response in the cutaneous circulation. J Appl Physiol. 95(2): 504-510, 2003.
Wilkins, B.W., Holowatz, L.A., Wong, B.J. and C.T. Minson. Nitric oxide is not permissive for cutaneous active vasodilatation in humans. J Physiol. 548(pt 3): 963-969, 2003.
Holowatz, L.A., Houghton, B.L., Wong, B.J., Wilkins, B.W., Harding, A.W., Kenney, W.L. and C.T. Minson. Nitric oxide and attenuated reflex cutaneous vasodilation in aged skin. Am J Physiol Heart Circ Physiol. 284(5): H1662-H1667, 2003.
Minson, C.T., Holowatz, L.A., Wong, B.J., Kenney, W.L. and B.W. Wilkins. Decreased nitric oxide and axon reflex mediated cutaneous vasodilation with age during local heating. J Appl Physiol. 93(5): 1644-1649, 2002.
Watts, P., Daggett, M., Gallagher, P.M. and B. Wilkins. Metabolic responses during sport rock climbing and the effects of active versus passive recovery. Int J Sports Med. 21: 185-190, 2000.
Watts, P., Coleman, B., Clure, C., Daggett, M., Gallagher, P., Sustrich, P. and B. Wilkins. Metabolic and cardiovascular responses during work on a high ropes course. J Sports Med Phys Fit. 39(1): 37-41, 1999.
Dr. Wilkins has a diverse scientific background within both industry and academic research settings. His current research focus explores factors that can alter the balance of oxygen supply and demand during exercise and their impact on muscle bioenergetics, oxygen uptake kinetics, fatigue, and human performance. Previous research topics include blood pressure regulation, control of muscle blood flow during exercise, thermoregulation, and physiological models predicting athlete performance. There are a variety (numerous) student research ideas utilizing tools like near infrared spectroscopy (NIRS), beat by beat blood pressure, oxygen uptake, blood lactate analysis, and EMG (to name a few) to explore questions around how altered mechanics contribute to muscle fatigue, changing muscle activation patterns with limited muscle oxygen supply, how disrupting the balance of oxygen supply and demand alters bioenergetics, and many others. Dr. Wilkins has a keen interest in how all these interrelationships can impact human performance.